Some R282 billion was pledged across the four investment conferences.
Nevertheless, Ramathuba said the R66 billion invested in the province has had a significant impact on the provincial economy and has so far led to the creation of over 20,000 jobs across various sectors.
On Wednesday, Ramathuba launched the fifth edition of the Limpopo Investment Conference in Polokwane.
"Let's take the 2024 Limpopo Investment Conference for example: It catalysed R120.3 billion in new investment pledges, showcasing the growing confidence in Limpopo's investment climate," she said.
"Currently, projects worth R19.2 billion are progressing well, including notable developments such as Ivanplats and Generic Core Sustainable Energy, which exemplify our province's potential in mining and renewable energy sectors.'
Ramathuba said the 2025 edition will signify the government's commitment to sustaining growth and development in Limpopo.
"This conference will also unveil the Limpopo Investment Book 2025, which will outline over R32 billion in investment opportunities across diverse sectors, reaffirming Limpopo's readiness as a prime investment destination."